Cloned (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
- |
Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Bos taurus | |
1,10-phenanthroline | - |
Rattus norvegicus | |
Aminopropylmercapto succinic acid | - |
Bos taurus | |
Aminopropylmercapto succinic acid | - |
Rattus norvegicus | |
Guanidinoethylmercaptosuccinic acid | - |
Bos taurus | |
Guanidinoethylmercaptosuccinic acid | - |
Rattus norvegicus | |
p-chloromercuriphenyl sulfonate | - |
Bos taurus | |
p-chloromercuriphenyl sulfonate | - |
Rattus norvegicus | |
sulfhydryl reagents | - |
Bos taurus | |
sulfhydryl reagents | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rattus norvegicus | 16020 | - |
membrane | - |
Bos taurus | 16020 | - |
secretory granule | - |
Rattus norvegicus | 30141 | - |
secretory granule | chromaffin granules | Bos taurus | 30141 | - |
soluble | - |
Rattus norvegicus | - |
- |
soluble | - |
Bos taurus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | activates | Rattus norvegicus | |
Co2+ | activates | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | highly specific for C-terminal basic amino acids Arg in decreasing order: Arg, Lys, His, does not cleave other amino acids | ? | - |
? | |
additional information | Bos taurus | highly specific for C-terminal basic amino acids Arg in decreasing order: Arg, Lys, His, does not cleave other amino acids | ? | - |
? | |
additional information | Rattus norvegicus | releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin, associated with the biosynthesis of many peptide neurotransmitters and hormones | ? | - |
? | |
additional information | Bos taurus | releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin, associated with the biosynthesis of many peptide neurotransmitters and hormones | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | glycoprotein | Rattus norvegicus |
side-chain modification | glycoprotein | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal medulla | - |
Rattus norvegicus | - |
adrenal medulla | - |
Bos taurus | - |
brain | - |
Rattus norvegicus | - |
brain | - |
Bos taurus | - |
heart | low activity | Rattus norvegicus | - |
heart | low activity | Bos taurus | - |
hypophysis | - |
Rattus norvegicus | - |
hypophysis | - |
Bos taurus | - |
additional information | 2 forms: soluble and membrane-bound are present in most tissues | Rattus norvegicus | - |
additional information | 2 forms: soluble and membrane-bound are present in most tissues | Bos taurus | - |
pancreas | low activity | Rattus norvegicus | - |
pancreas | low activity | Bos taurus | - |
spleen | low activity | Rattus norvegicus | - |
spleen | low activity | Bos taurus | - |
testis | low activity | Rattus norvegicus | - |
testis | low activity | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(Met)enkephalin-Arg + H2O | - |
Rattus norvegicus | Tyr-Gly-Gly-Phe-Met + Arg | - |
? | |
(Met)enkephalin-Arg + H2O | - |
Bos taurus | Tyr-Gly-Gly-Phe-Met + Arg | - |
? | |
(Met)enkephalin-Lys + H2O | - |
Rattus norvegicus | Tyr-Gly-Gly-Phe-Met + Lys | - |
? | |
(Met)enkephalin-Lys + H2O | - |
Bos taurus | Tyr-Gly-Gly-Phe-Met + Lys | - |
? | |
additional information | highly specific for C-terminal basic amino acids in decreasing order: Arg, Lys,His, does not cleave other amino acids | Rattus norvegicus | ? | - |
? | |
additional information | highly specific for C-terminal basic amino acids in decreasing order: Arg, Lys,His, does not cleave other amino acids | Bos taurus | ? | - |
? | |
additional information | releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin | Rattus norvegicus | ? | - |
? | |
additional information | releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin | Bos taurus | ? | - |
? | |
additional information | highly specific for C-terminal basic amino acids Arg in decreasing order: Arg, Lys, His, does not cleave other amino acids | Rattus norvegicus | ? | - |
? | |
additional information | highly specific for C-terminal basic amino acids Arg in decreasing order: Arg, Lys, His, does not cleave other amino acids | Bos taurus | ? | - |
? | |
additional information | releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin, associated with the biosynthesis of many peptide neurotransmitters and hormones | Rattus norvegicus | ? | - |
? | |
additional information | releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin, associated with the biosynthesis of many peptide neurotransmitters and hormones | Bos taurus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | 6 | - |
Rattus norvegicus |
5 | 6 | - |
Bos taurus |